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Amoxicillin; Clavulanic Acid Extended-Release Tablets

What is this medicine?

AMOXICILLIN; CLAVULANIC ACID (a mox i SILL in; KLAV yoo lan ic AS id) is a penicillin antibiotic. It treats some infections caused by bacteria. It will not work for colds, the flu, or other viruses.

How should I use this medicine?

Take this drug by mouth. Take it as directed on the prescription label at the same time every day. Take it with food at the start of a meal or snack. Do not cut, crush or chew this drug. Swallow the tablets whole. Take all of this drug unless your health care provider tells you to stop it early. Keep taking it even if you think you are better.

Talk to your health care provider about the use of this drug in children. While it may be prescribed for selected conditions, precautions do apply.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • breathing problems

  • dark urine

  • fever or chills, sore throat

  • redness, blistering, peeling, or loosening of the skin, including inside the mouth

  • seizures

  • trouble passing urine or change in the amount of urine

  • unusual bleeding, bruising

  • unusually weak or tired

  • white patches or sores in the mouth or throat

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • diarrhea

  • dizziness

  • headache

  • nausea, vomiting

  • stomach upset

  • vaginal or anal irritation

What may interact with this medicine?

  • allopurinol

  • anticoagulants

  • birth control pills

  • methotrexate

  • probenecid

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Where should I keep my medicine?

Keep out of the reach of children and pets.

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Throw away any unused drug after the expiration date.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • bowel disease, like colitis

  • kidney disease

  • liver disease

  • mononucleosis

  • an unusual or allergic reaction to amoxicillin, penicillin, cephalosporin, other antibiotics, clavulanic acid, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

What should I watch for while using this medicine?

Tell your doctor or healthcare provider if your symptoms do not improve.

This medicine may cause serious skin reactions. They can happen weeks to months after starting the medicine. Contact your healthcare provider right away if you notice fevers or flu-like symptoms with a rash. The rash may be red or purple and then turn into blisters or peeling of the skin. Or, you might notice a red rash with swelling of the face, lips or lymph nodes in your neck or under your arms.

Do not treat diarrhea with over the counter products. Contact your doctor if you have diarrhea that lasts more than 2 days or if it is severe and watery.

If you have diabetes, you may get a false-positive result for sugar in your urine. Check with your doctor or healthcare provider.

Birth control pills may not work properly while you are taking this medicine. Talk to your doctor about using an extra method of birth control.

NOTE:This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider. Copyright© 2020 Elsevier
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